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One major aspect of emergency management and treatment of heart attacks and ischemic strokes that the general public is unaware of, is a drug called TPA (tissue plasminogen activator). TPA will accelerate clot breakdown and help reestablish blood flow to an ischemic area. For this to be beneficial, TPA needs to be administered within the first three hours after the stroke. According to the American Heart Association (AHA), if TPA is given within the first 3 hours of a stroke, it may reduce permanent disability. If given within 12 hours of the onset of a heart attack, the person has a better chance for survival and recovery.

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